What do we really know about newborn infant pain?

Superior Capsule Reconstruction: What Do We Know?

The management of irreparable rotator cuff tears remains challenging. Since its introduction by Mihata in 2012, superiorcapsule reconstruction (SCR) has grown in popularity at an astonishingly rapid rate. The aim of this article is to providea comprehensive review of the available literature, in order to highlight what has so far been published on SCR,covering all aspects including biomechanica...

Do We Know What We Do not Know? A Response to Celine Bonnet

What do we really know about the Sun-climate connection?

The Earth's climate has always been changing. This is documented in historical as well as in geological records. The reasons for these changes, however, have always been subject to discussions and are still not well understood. In addition to natural climate changes the risk of human influence on climate has recently been seriously considered by the Intergovernmental Panel on Climate Change. An...

Pleomorphic xanthoastrocytoma: what do we really know about it?

BACKGROUND Pleomorphic xanthoastrocytomas (PXA) may recur and demonstrate aggressive clinical behavior with a mortality rate between 15% and 20%. To the authors' knowledge, no histopathologic features currently are known to reliably predict recurrence or tumor progression. METHODS The study was based on 71 cases with available information regarding clinical and therapeutic data and follow-up....

What do we really know about "tinea incognita"?

The term "tinea incognita" refers to diverse clinical presentation of mycotic infections modified by inappropriate use of topical or systemic corticosteroids. A 67-year-old male patient with a five-year history of generalized erythematous plaques on the trunk and extremities, previously treated with topical corticosteroids, is described. The lesions mainly showed a psoriasiform, some eczematous...